Application Research
LYU Lin-fang, ZHANG Han-yang, LI Cong-xin
Objective To observe the distribution of multi-drug resistant organisms (MDRO) in a grade 3A hospital, so as to provide data for prevention policies and measures. Methods Retrospective survey was conducted to monitor and analyze the MDRO infection status and characteristics of hospitalized patients in the hospital from 2018 to 2022. Results A totel of 14 597 strains of pathogenic bacteria were detected in 5 years, among which 2 819 strains of MDRO were isolated, with the detection rate of 19.31%. MDRO was mainly composed of carbapenem resistant strains, and the detection rate of carbapenem resistant Acinetobacter baumannii (CR-AB), methicillin-resistant Staphylococcus aureus (MRSA), carbapenem resistant Pseudomonas aeruginosa (CR-PA), carbapenem resistant Klebsiella pneumoniae (CR-KPN), and carbapenem resistant Enterobacterium (CRE) was 54.46%, 37.86%, 35.84%, 25.17%, and 12.84%, respectively. The main infection sites caused by MDRO were lower respiratory tract, blood, and urinary tract, accounting for 51.15%, 12.79%, and 12.46%, respectively. Infection mainly occured in ICU, general surgery, and hematology, accounting for 40.33%, 13.44%, and 11.48%, respectively. Conclusions The MDRO detection rate in this hospital is relatively high, however, the infection rate shows a downward trend. It is necessary to strengthen the monitoring and prevention and control management of high-risk departments and high-risk sites of MDRO hospital infection.